Description

(1R,2S)-2-[(1,3-Dihydro-1,3-Dioxo-2H-Isoindol-2-Yl)Methyl]-N,n-Diethyl-1-Phenylcyclopropanecarboxamide-D10 is a deuterated isotopologue of a complex organic compound featuring a cyclopropane and phthalimide core structure. This product is of significant value for pharmaceutical research and development, particularly in the fields of drug metabolism and pharmacokinetics (DMPK) studies. It serves as a critical internal standard or tracer in mass spectrometry-based analytical methods, enabling precise quantification and mechanistic investigations. Industries requiring high-fidelity analytical standards, such as pharmaceutical R&D, contract research organizations (CROs), and advanced material science, are the primary target markets for this specialized chemical.

Application

• Internal Standard for LC-MS/MS Analysis: Used as a stable, isotopically labeled internal standard for the accurate quantification of its non-deuterated counterpart in biological matrices.
• Drug Metabolism Studies (DMPK): Employed in absorption, distribution, metabolism, and excretion (ADME) research to track metabolic pathways and improve drug candidate profiles.
• Pharmaceutical Impurity Profiling: Aids in the identification and quantification of process-related impurities or degradants during drug substance development.
• Biomarker Research: Facilitates precise measurement in proteomics and metabolomics studies where high specificity and sensitivity are required.
• Chemical Reference Standard: Serves as a certified reference material (CRM) for method validation and quality control in analytical laboratories.
• Mechanistic Organic Chemistry Research: Used as a tool to study reaction mechanisms, isotopic effects, and molecular interactions in academic and industrial settings.

Basic Information

Item	Detail
Product Name	(1R,2S)-2-[(1,3-Dihydro-1,3-Dioxo-2H-Isoindol-2-Yl)Methyl]-N,n-Diethyl-1-Phenylcyclopropanecarboxamide-D10
CAS No.	1246818-55-2
Molecular Formula	C24H25D10N3O3
Molecular Weight	Approx. 419.62 g/mol
Synonyms	N,N-Diethyl-2-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]-1-phenylcyclopropanecarboxamide-d10; Deuterated (1R,2S)-2-(Phthalimidomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide; (1R,2S)-2-[(1,3-Dioxoisoindolin-2-yl)methyl]-N,N-diethyl-1-phenylcyclopropane-1-carboxamide-d10; Cyclopropanecarboxamide-D10 derivative; Isotopically Labeled Phthalimide Derivative; D10-Labeled Internal Standard; [D10]-(1R,2S)-2-(Phthalimidomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch of (1R,2S)-2-[(1,3-Dihydro-1,3-Dioxo-2H-Isoindol-2-Yl)Methyl]-N,n-Diethyl-1-Phenylcyclopropanecarboxamide-D10 is characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry to confirm identity, chemical purity, and isotopic enrichment. We adhere to strict quality management protocols. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.