Description

Alexidine-D10 Dihydrochloride is a deuterated analog of the potent antimicrobial agent Alexidine dihydrochloride, where ten hydrogen atoms are replaced by deuterium. This isotopic labeling makes it a critical tool compound for pharmacokinetic, metabolic, and mechanistic studies, providing enhanced analytical sensitivity and stability. It is primarily utilized by pharmaceutical researchers, contract research organizations (CROs), and academic institutions engaged in advanced drug development, particularly for investigating anti-infective and antiseptic agents.

Application

• As an internal standard for the precise quantification of Alexidine in biological matrices using LC-MS/MS.
• In drug metabolism and pharmacokinetics (DMPK) studies to trace metabolic pathways and assess bioavailability.
• For mechanistic research on bis-biguanide compounds and their interactions with biological targets.
• In the development and validation of analytical methods for regulatory compliance and quality control.
• As a key material in preclinical research for novel antimicrobial and antiseptic formulations.

Basic Information

Product Name	Alexidine-D10 Dihydrochloride
CAS No.	1246818-47-2
Molecular Formula	C26H38D10Cl2N10
Molecular Weight	Contact for details
Synonyms	Alexidine-d10 Dihydrochloride; 1,1'-[1,6-Hexanediylbis[imino(1,1-deuterio-2,1-ethanediyl)]]bis[5-(2-ethylhexyl)biguanide] Dihydrochloride; Deuterated Alexidine Dihydrochloride; Alexidine (D10) Dihydrochloride; 1,1'-Hexamethylenebis[5-(2-ethylhexyl)biguanide]-d10 Dihydrochloride; Bisbiguanide-d10 Dihydrochloride
EINECS	Contact for details

Quality Control

Our Alexidine-D10 Dihydrochloride is manufactured under strict quality systems to ensure high isotopic purity and chemical integrity, suitable for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic enrichment, chemical purity, and absence of critical impurities. We adhere to cGMP principles for research chemicals, ensuring traceability and consistency for your critical development work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Isotopic Purity (Deuterium Enrichment)	≥ 98 atom % D
Chemical Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.