Description

4-(2,2,3,3,4,4,5,5,6,6-Decadeuteriopiperidin-1-Yl)-1-[4-(4-Fluorophenyl)-4-Oxobutyl]Piperidine-4-Carboxamide is a deuterated piperidine derivative, a high-value synthetic intermediate designed for advanced research and development. This compound is critical for applications requiring stable isotope labeling, such as in the creation of internal standards for mass spectrometry and the study of metabolic pathways. It is primarily utilized by pharmaceutical R&D teams, analytical laboratories, and specialized chemical synthesis units working on novel drug discovery and bioanalytical method development.

Application

• Pharmaceutical Research: Serves as a key deuterium-labeled intermediate in the synthesis of novel drug candidates, particularly for pharmacokinetic (PK) and absorption, distribution, metabolism, and excretion (ADME) studies.
• Analytical Chemistry: Used as an internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS) for the precise quantification of pharmaceutical compounds and their metabolites.
• Metabolic Pathway Tracing: Enables the study of biochemical pathways and drug metabolism in vivo through stable isotope labeling techniques.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and lead optimization processes where isotopic labeling is required.
• Contract Research Organizations (CROs): Essential for bioanalytical service providers offering specialized quantification and metabolite identification services to the pharmaceutical industry.
• Academic Research: Used in university and institutional labs for cutting-edge research in chemical biology, pharmacology, and analytical method development.

Basic Information

Product Name	4-(2,2,3,3,4,4,5,5,6,6-Decadeuteriopiperidin-1-Yl)-1-[4-(4-Fluorophenyl)-4-Oxobutyl]Piperidine-4-Carboxamide
CAS No.	1246818-04-1
Molecular Formula	C21H20D10FN3O2
Molecular Weight	Contact for details
Synonyms	1-[4-(4-Fluorophenyl)-4-oxobutyl]-4-(2,2,3,3,4,4,5,5,6,6-decadeuteriopiperidin-1-yl)piperidine-4-carboxamide; 4-(Perdeuteriopiperidin-1-yl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidine-4-carboxamide; Deuterated Piperidine Carboxamide Derivative; CAS 1246818-04-1; 4-Carboxamide, 1-[4-(4-fluorophenyl)-4-oxobutyl]-4-(2,2,3,3,4,4,5,5,6,6-decadeuterio-1-piperidinyl)piperidine
EINECS	Contact for details

Quality Control

Our 4-(2,2,3,3,4,4,5,5,6,6-Decadeuteriopiperidin-1-Yl)-1-[4-(4-Fluorophenyl)-4-Oxobutyl]Piperidine-4-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and MS, to ensure high isotopic purity and chemical identity. Certificates of Analysis (COA) detailing batch-specific results for assay, isotopic enrichment, and impurity profiles are provided to guarantee traceability and consistency for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Isotopic Purity (MS)	≥ 98.0 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.