Description

Phenmetrazine-D5 Hydrochloride is a stable isotope-labeled internal standard of the pharmaceutical compound phenmetrazine, specifically designed for analytical precision. This high-purity reference material is critical for ensuring accurate quantification and method validation in sensitive analytical workflows. It is primarily utilized by research, forensic, and pharmaceutical development laboratories engaged in pharmacokinetic studies, doping control, and metabolite profiling.

Application

• Quantitative Analytical Reference Standard: Serves as an essential internal standard for the precise quantification of phenmetrazine and its metabolites in biological matrices using LC-MS/MS and GC-MS.
• Forensic Toxicology & Doping Control: Used in method development and routine testing for the accurate identification and measurement of phenmetrazine in urine, blood, and hair samples for legal and anti-doping purposes.
• Pharmacokinetic & Metabolism Studies: Enables reliable tracking of drug absorption, distribution, metabolism, and excretion (ADME) in clinical and pre-clinical research.
• Method Development & Validation: Provides a critical tool for developing, optimizing, and validating robust analytical methods, ensuring compliance with guidelines from agencies like the FDA and EMA.
• Pharmaceutical Quality Control: Supports impurity profiling and assay development for pharmaceutical formulations containing related compounds.

Basic Information

Product Name	Phenmetrazine-D5 Hydrochloride
CAS No.	1246817-91-3
Molecular Formula	C11H10D5NO·HCl
Molecular Weight	221.76 g/mol
Synonyms	3-Methyl-2-phenylmorpholine-2,3,4,5,6-d5 Hydrochloride; Phenmetrazine-d5 HCl; Deuterated Phenmetrazine Hydrochloride; (RS)-3-Methyl-2-phenylmorpholine-2,3,4,5,6-d5 hydrochloride; 2-Phenyl-3-methyltetrahydro-1,4-oxazine-2,3,4,5,6-d5 hydrochloride
EINECS	Contact for details

Quality Control

Our Phenmetrazine-D5 Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR, HPLC, and MS, to confirm isotopic purity, chemical purity, and structural identity. We provide a comprehensive Certificate of Analysis (COA) with each shipment, detailing all test results and specifications. Our quality commitment ensures the material meets the stringent requirements for research and regulated analytical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under dry conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity	≥ 98 atom % D
Chemical Purity	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.