Description

Carboxymethoxyamine-D2 Hemihydrochloride is a high-purity, deuterated derivative of carboxymethoxyamine, specifically designed for advanced research and development applications. This compound is critical for studies requiring isotopic labeling, such as metabolic pathway tracing, pharmacokinetics, and mass spectrometry-based analytical method development. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions focused on drug discovery and analytical chemistry.

Application

• Isotopic Labeling Agent: Used as a deuterium-labeled reagent for the synthesis of isotopically labeled compounds in pharmaceutical research.
• Mass Spectrometry (MS) Standards: Serves as an internal standard or reference material in LC-MS and GC-MS analyses to improve quantification accuracy.
• Metabolic Studies: Employed in tracing studies to investigate drug metabolism and biochemical pathways.
• Pharmaceutical Intermediate: Acts as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs) and prodrugs.
• Analytical Method Development: Used to validate and calibrate analytical methods for the detection of amine-containing compounds.
• Bioconjugation Chemistry: Utilized in the modification of biomolecules for research in chemical biology and biophysics.

Basic Information

Product Name	Carboxymethoxyamine-D2 Hemihydrochloride
CAS No.	1246817-66-2
Molecular Formula	C₂H₃D₂NO₃·½HCl
Molecular Weight	Contact for details
Synonyms	O-(Carboxymethyl)hydroxylamine-d2 hemihydrochloride; Aminooxyacetic acid-d2 hemihydrochloride; AOAA-d2 hemihydrochloride; (Aminooxy)acetic acid-d2 hemihydrochloride; Carboxymethoxylamine-d2 hemihydrochloride; Deuterated carboxymethoxyamine hemihydrochloride; Glycine, N-(oxy)-, D2- hemihydrochloride
EINECS	Contact for details

Quality Control

Our Carboxymethoxyamine-D2 Hemihydrochloride is manufactured under strict quality control protocols to ensure high chemical purity and isotopic enrichment. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as purity (by HPLC/NMR), deuterium enrichment, and impurity profile. We adhere to cGMP principles for research chemicals, ensuring traceability, consistency, and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Deuterium Enrichment (NMR/MS)	≥ 98 atom % D
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.