Description

Ticlopidine-D4 is a deuterated analog of the antiplatelet agent Ticlopidine, specifically labeled with four deuterium atoms. This stable isotope-labeled compound is essential for use as an internal standard in quantitative bioanalytical methods, ensuring the highest accuracy and reliability in pharmacokinetic and metabolic studies. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and analytical testing facilities engaged in drug development and regulatory compliance work.

Application

• Internal Standard for LC-MS/MS: Critical for the precise quantification of Ticlopidine and its metabolites in biological matrices like plasma, serum, and urine.
• Drug Metabolism and Pharmacokinetics (DMPK): Used in absorption, distribution, metabolism, and excretion (ADME) studies to track drug fate.
• Clinical Research: Supports bioequivalence and therapeutic drug monitoring studies requiring high analytical precision.
• Pharmaceutical Quality Control: Aids in method development and validation for impurity profiling and assay of drug substances and products.
• Forensic Toxicology: Employed in confirmatory analytical procedures for the accurate detection of Ticlopidine.

Basic Information

Product Name	Ticlopidine-D4
CAS No.	1246817-49-1
Molecular Formula	C14H10D4ClNS
Molecular Weight	267.80 g/mol (for C14H10D4ClNS)
Synonyms	5-[(2-Chlorophenyl)methyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridine-2,3,4,5-d4; Ticlopidine (phenyl-d4); Ticlopidine-d4; Deuterated Ticlopidine; Ticlopidine Internal Standard; 2,3,4,5-Tetradeutero-5-[(2-chlorophenyl)methyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridine
EINECS	Contact for details

Quality Control

Every batch of Ticlopidine-D4 is manufactured and analyzed under strict quality management systems. We guarantee high chemical and isotopic purity, with comprehensive testing performed using advanced techniques including NMR, HPLC, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting batch-specific data for identity, purity (HPLC assay), isotopic enrichment, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider keeping the product at 2-8°C. Handle and store in accordance with good laboratory practices.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Deuterium Content)	≥ 98 atom % D
Chemical Purity (by HPLC)	≥ 99.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.