Description

5,6-Diamino-3-Methyluracil-D3 is a deuterated derivative of a key uracil-based heterocyclic compound, serving as a crucial stable isotope-labeled building block. This product matters for its role in enabling advanced research and development in pharmaceutical and analytical chemistry, where precise molecular tracking is essential. It is primarily needed by researchers and manufacturers in the pharmaceutical industry for applications such as the synthesis of labeled drug candidates, metabolites, and internal standards for mass spectrometry.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of deuterium-labeled pharmaceutical compounds, including xanthine derivatives and potential kinase inhibitors.
• Metabolite Synthesis: Used in the preparation of stable isotope-labeled metabolites for drug metabolism and pharmacokinetics (DMPK) studies.
• Mass Spectrometry Internal Standards: Serves as a precursor for high-purity internal standards in LC-MS/MS and GC-MS analysis, improving quantitative accuracy.
• Biochemical Research: Employed in mechanistic studies and tracer experiments to investigate biological pathways and enzyme functions.
• Chemical Reference Standard: Provides a certified reference material for quality control and method validation in analytical laboratories.

Basic Information

Product Name	5,6-Diamino-3-Methyluracil-D3
CAS No.	1246816-74-9
Molecular Formula	C5H4D3N4O2
Molecular Weight	158.15 g/mol
Synonyms	3-Methyl-5,6-diaminouracil-d3; 5,6-Diamino-1,3-dimethyl-2,4(1H,3H)-pyrimidinedione-d3; 5,6-Diamino-3-methyl-1H-pyrimidine-2,4-dione-d3; Deuterated 5,6-Diamino-3-methyluracil; 3-Methyl-5,6-diamino-2,4(1H,3H)-pyrimidinedione-d3; DAU-D3; 5,6-Diamino-3-methyl-2,4-dihydroxypyrimidine-d3
EINECS	Contact for details

Quality Control

Our 5,6-Diamino-3-Methyluracil-D3 is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for chemical purity and NMR for isotopic enrichment verification, to ensure compliance with research and development standards. A comprehensive Certificate of Analysis (COA) detailing purity, isotopic purity, and identity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.