Description

N,n-Bis(2-Chloro-2,2-Dideuterioethyl)-4-Hydroperoxy-2-Oxo-1,3,2$L^{5}-Oxazaphosphinan-2-Amine is a specialized deuterated and peroxidized oxazaphosphinane derivative, representing a high-value synthetic intermediate. Its core value lies in its unique molecular architecture, which incorporates deuterium atoms and a hydroperoxy functional group, making it a critical precursor for advanced research and development. This compound is essential for scientists and manufacturers in the pharmaceutical and agrochemical sectors, particularly for applications in mechanistic studies, metabolic pathway tracing, and the synthesis of novel bioactive molecules.

Application

• Pharmaceutical Research & Development: As a deuterated intermediate for synthesizing isotopically labeled drug candidates to study pharmacokinetics, metabolism, and stability.
• Mechanistic Organic Chemistry: Utilized as a probe or reagent in reaction mechanism studies, leveraging the kinetic isotope effect (KIE) of deuterium.
• Agrochemical Synthesis: Serves as a key building block for developing novel, labeled pesticides or herbicides with enhanced environmental or metabolic profiles.
• Biochemical Tracers: Used in the preparation of labeled compounds for mass spectrometry-based proteomic or metabolomic analysis.
• Material Science Precursor: Potential use in synthesizing specialized polymers or ligands where the peroxidized moiety can initiate or modify polymerization.
• Academic Research: A valuable tool for universities and research institutes exploring new synthetic methodologies involving peroxides and phosphorus-nitrogen heterocycles.

Basic Information

Product Name	N,n-Bis(2-Chloro-2,2-Dideuterioethyl)-4-Hydroperoxy-2-Oxo-1,3,2$L^{5}-Oxazaphosphinan-2-Amine
CAS No.	1246816-71-6
Molecular Formula	C7H9D4Cl2N2O4P
Molecular Weight	Contact for details
Synonyms	4-Hydroperoxy-2-oxo-N,N-bis(2-chloro-2,2-dideuteroethyl)-1,3,2$l^5-oxazaphosphinan-2-amine; Deuterated Cyclophosphamide Peroxide Analog; 2-Amino-4-hydroperoxy-2-oxo-N,N-bis(2-chloro-2,2-dideuteroethyl)-1,3,2$l^5-oxazaphosphinane; Bis(2-chloro-2,2-dideuteroethyl) 4-hydroperoxy-2-oxo-1,3,2$l^5-oxazaphosphinan-2-ylamine; 1246816-71-6; Deuterated Ifosfamide Peroxide Derivative; Oxazaphosphinane-2-amine, N,N-bis(2-chloro-2,2-dideuteroethyl)-4-hydroperoxy-2-oxo-
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality protocols to ensure batch-to-batch consistency and purity for research applications. Quality is verified through analytical techniques including NMR (¹H, ¹³C, ³¹P), HPLC, and mass spectrometry to confirm structural identity, isotopic enrichment (D%), and chemical purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) in a dedicated freezer for peroxidized and light-sensitive compounds. Allow the sealed container to reach room temperature before opening to prevent moisture condensation. Keep away from heat, sparks, open flames, and reducing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Deuterium Incorporation (MS/NMR)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Peroxide Assay (Titration)	Contact for details
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.