Description

1,8-Dihydroxyanthraquinone-D6 is a deuterated derivative of the important anthraquinone dye intermediate, 1,8-dihydroxyanthraquinone. This compound is specifically valued for its role as a stable isotope-labeled internal standard in analytical chemistry, providing enhanced accuracy and reliability in quantitative mass spectrometry. It is primarily utilized by research institutions, pharmaceutical companies, and analytical laboratories engaged in method development, pharmacokinetic studies, and metabolic research where precise quantification of the non-deuterated parent compound is critical.

Application

• Internal Standard for LC-MS/MS: Serves as a critical deuterated internal standard for the accurate quantification of 1,8-dihydroxyanthraquinone and related metabolites in complex biological matrices.
• Pharmaceutical Research: Used in drug metabolism and pharmacokinetics (DMPK) studies to track the absorption, distribution, metabolism, and excretion of anthraquinone-based drug candidates.
• Analytical Method Development: Essential for developing and validating robust, high-precision analytical methods in compliance with regulatory guidelines (e.g., FDA, ICH).
• Biomarker Analysis: Facilitates the precise measurement of anthraquinone derivatives as potential biomarkers in clinical and environmental studies.
• Chemical Synthesis Research: Employed as a labeled starting material or reference compound in synthetic chemistry to study reaction mechanisms or pathways.
• Quality Control in Manufacturing: Acts as a reference standard for the quality assurance of non-labeled 1,8-dihydroxyanthraquinone in industrial production.

Basic Information

Product Name	1,8-Dihydroxyanthraquinone-D6
CAS No.	1246816-27-2
Molecular Formula	C14H2D6O4
Molecular Weight	~246.26 g/mol
Synonyms	1,8-Dihydroxy-9,10-anthraquinone-D6; 1,8-Dihydroxyanthraquinone (hexadeuterated); Chrysazin-D6; Danthron-D6; 1,8-Dihydroxy-9,10-anthracenedione-D6; Isotopic Labeled 1,8-DHAQ; [D6]-1,8-Dihydroxyanthraquinone
EINECS	Contact for details

Quality Control

Our 1,8-Dihydroxyanthraquinone-D6 is manufactured under strict quality control protocols to ensure high isotopic purity and chemical integrity, suitable for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as isotopic enrichment, chemical purity, and absence of interfering impurities. We adhere to relevant industry standards for stable isotope-labeled compounds to guarantee batch-to-batch consistency and reliability for your research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Orange to red powder
Identification (IR)	Conforms to structure
Isotopic Purity (D6)	≥ 98 atom % D
Chemical Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.