Description

2,3,5,6-Tetradeuterio-4-[4-[4-(Methoxymethoxy)Phenyl]Piperazin-1-Yl]Aniline is a deuterated derivative of a key aniline-piperazine intermediate, offering enhanced stability and unique metabolic properties for advanced research. This compound is critical for the development of deuterated pharmaceuticals, where the strategic replacement of hydrogen with deuterium can significantly improve drug efficacy and safety profiles. It serves as a vital building block for medicinal chemists and researchers in pharmaceutical R&D, agrochemical development, and advanced material science.

Application

• Deuterated Pharmaceutical Intermediate: A crucial precursor for synthesizing deuterium-labeled drug candidates in drug discovery and development programs.
• Metabolic & Pharmacokinetic (PK/PD) Studies: Used as an internal standard or tracer in mass spectrometry for precise quantification and metabolic pathway analysis.
• Agrochemical Research: Employed in the development of novel, deuterated active ingredients to potentially enhance environmental stability and biological activity.
• Organic Light-Emitting Diode (OLED) Materials: Acts as a specialized intermediate for synthesizing deuterated charge-transport or emissive layer materials to improve device lifetime and efficiency.
• Chemical Biology Probes: Utilized to create isotopically labeled probes for studying biological mechanisms and protein-ligand interactions.
• Reference Standard: Serves as a high-purity analytical standard for quality control and regulatory submissions in pharmaceutical manufacturing.

Basic Information

Product Name	2,3,5,6-Tetradeuterio-4-[4-[4-(Methoxymethoxy)Phenyl]Piperazin-1-Yl]Aniline
CAS No.	1246816-20-5
Molecular Formula	C18H18D4N3O2
Molecular Weight	318.42 g/mol
Synonyms	4-(4-(4-(Methoxymethoxy)phenyl)piperazin-1-yl)-2,3,5,6-tetradeuterioaniline; d4-4-[4-[4-(Methoxymethoxy)Phenyl]Piperazin-1-Yl]Aniline; Deuterated 4-(4-(4-(Methoxymethoxy)phenyl)piperazin-1-yl)aniline; 2,3,5,6-Tetradeutero-4-[4-[4-(methoxymethoxy)phenyl]-1-piperazinyl]benzenamine; 1-[4-(Methoxymethoxy)phenyl]-4-(4-amino-2,3,5,6-tetradeuteriophenyl)piperazine
EINECS	Contact for details

Quality Control

Our deuterated chemicals are produced under strict quality control protocols to ensure high isotopic purity and chemical integrity, essential for sensitive research applications. Each batch is characterized by advanced analytical techniques including NMR, HPLC, and Mass Spectrometry. A comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (D-content), chemical purity, and identification is provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light). For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Deuterium Content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.