Description

Rolicyclidine-D5 Hydrochloride CAS NO 1246815-30-4 is a deuterated analog of the arylcyclohexylamine compound, rolicyclidine, where five hydrogen atoms are replaced with deuterium, supplied as its hydrochloride salt. This isotopically labeled compound is of critical importance for use as an internal standard in analytical chemistry, ensuring the accuracy and reliability of quantitative measurements. It is primarily required by research and development laboratories, forensic science institutions, and pharmaceutical companies engaged in method development, pharmacokinetic studies, and substance identification.

Application

• Analytical Reference Standard: Serves as a certified internal standard for the precise quantification of rolicyclidine and related compounds in complex matrices using LC-MS/MS and GC-MS.
• Forensic Toxicology: Essential for confirmatory testing and method validation in forensic laboratories analyzing biological samples for novel psychoactive substances (NPS).
• Pharmacokinetic Research: Used in drug metabolism and pharmacokinetic (DMPK) studies to track the absorption, distribution, metabolism, and excretion of the parent compound.
• Method Development & Validation: A key component in developing and validating robust, high-sensitivity analytical methods in compliance with regulatory guidelines (e.g., FDA, EMA).
• Pharmaceutical Impurity Profiling: Aids in the identification and quantification of potential impurities or degradation products in pharmaceutical research.
• Clinical Research: Supports clinical studies requiring highly accurate bioanalytical data for investigational compounds.

Basic Information

Product Name	Rolicyclidine-D5 Hydrochloride
CAS No.	1246815-30-4
Molecular Formula	C18H24D5NO.HCl
Molecular Weight	Contact for details
Synonyms	1-(1-Phenylcyclohexyl)-3-pyrrolidinol-D5 Hydrochloride; PCPy-D5 Hydrochloride; Rolicyclidine-d5 HCl; (RS)-1-(1-Phenylcyclohexyl)pyrrolidin-3-ol-d5 Hydrochloride; 3-Hydroxy-PCP-d5 Hydrochloride; PHP-d5 Hydrochloride; Phenylcyclohexylpyrrolidinol-D5 Hydrochloride
EINECS	Contact for details

Quality Control

Our Rolicyclidine-D5 Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR, HPLC, and mass spectrometry, to confirm identity, isotopic purity (D5), and chemical purity. We provide a comprehensive Certificate of Analysis (COA) with each shipment, detailing batch-specific results. Our quality commitment ensures the material meets the stringent requirements for use as a high-grade analytical reference standard.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98%
Isotopic Purity (D5)	≥98 atom % D
Water Content (KF)	≤2.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.