Description

Dapoxetine-D6 Hydrochloride is a deuterated isotopologue of dapoxetine hydrochloride, a compound of significant interest in analytical and pharmaceutical research. This labeled standard is essential for ensuring the accuracy and reliability of quantitative mass spectrometry analyses. It is primarily used by research scientists and quality control laboratories in the pharmaceutical and contract research organization (CRO) sectors for method development, validation, and bioanalytical studies.

Application

• Internal Standard for LC-MS/MS: Serves as a critical, non-interfering reference compound for the precise quantification of dapoxetine in complex biological matrices such as plasma, serum, and urine.
• Pharmacokinetic and Metabolism Studies: Enables accurate tracking of drug absorption, distribution, metabolism, and excretion (ADME) in preclinical and clinical research.
• Bioanalytical Method Development & Validation: Used as a benchmark to establish and validate sensitive, specific, and robust analytical methods compliant with regulatory guidelines (e.g., FDA, EMA).
• Drug Impurity Profiling and Stability Testing: Aids in the identification and quantification of potential degradants or metabolites during drug stability studies.
• Forensic and Clinical Toxicology: Supports accurate measurement of dapoxetine levels in forensic analysis and therapeutic drug monitoring.
• High-Purity Reference Material: Provides a certified reference standard for instrument calibration and ensuring data integrity in GLP/GMP environments.

Basic Information

Item	Detail
Product Name	Dapoxetine-D6 Hydrochloride
CAS No.	1246814-76-5
Molecular Formula	C21H17D6ClNO • HCl
Molecular Weight	371.34 g/mol (approx.)
Synonyms	Dapoxetine-d6 HCl; (S)-Dapoxetine-d6 Hydrochloride; (S)-N,N-Dimethyl-3-(naphthalen-1-yloxy)-1-phenylpropan-1-amine-d6 Hydrochloride; DAP-d6 HCl; Deuterated Dapoxetine Hydrochloride; 1-[3-(Dimethylamino-d6)propyl]-1-phenyl-3-(1-naphthyloxy)propylamine Hydrochloride; LY 210448-d6
EINECS	Contact for details

Quality Control

Our Dapoxetine-D6 Hydrochloride is manufactured under strict quality systems to ensure the highest isotopic and chemical purity required for analytical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing results from advanced analytical techniques including NMR, HPLC, and LC-MS. We ensure compliance with the stringent standards demanded for reference materials in regulated research environments.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (Mass Spectrometry)	Conforms
Purity (HPLC)	≥98.0%
Isotopic Purity (Deuterium Content)	≥98.0 atom % D
Chemical Purity (NMR)	Conforms
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.