Description

Fp-Biotin-D7 CAS NO 1246812-28-1 is a deuterium-labeled derivative of biotin, a vital coenzyme in carboxylation reactions. This high-purity, isotopically labeled compound is essential for use as an internal standard in quantitative mass spectrometry, ensuring unparalleled accuracy and reproducibility in analytical measurements. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions engaged in metabolomics, biomarker discovery, and pharmacokinetic studies.

Application

• Internal Standard for LC-MS/MS: Serves as a critical quantitative reference standard in liquid chromatography-tandem mass spectrometry for the precise measurement of biotin and related metabolites.
• Pharmaceutical Research & Development: Used in drug metabolism and pharmacokinetics (DMPK) studies to track and quantify biotin pathways in preclinical and clinical research.
• Biomarker Analysis & Metabolomics: Enables accurate quantification of biotin in complex biological matrices for disease biomarker identification and metabolic pathway analysis.
• Nutritional Science & Supplement Testing: Provides a reliable standard for the analysis of biotin content and bioavailability in fortified foods, dietary supplements, and nutritional formulations.
• Clinical Diagnostics: Supports the development and validation of high-sensitivity diagnostic assays for detecting biotin deficiencies or monitoring therapeutic levels.
• Stable Isotope Labeling Studies: Utilized in tracer studies to investigate biotin uptake, distribution, and metabolic fate in various biological systems.

Basic Information

Product Name	Fp-Biotin-D7
CAS No.	1246812-28-1
Molecular Formula	C10H9D7N2O3S
Molecular Weight	250.35 g/mol
Synonyms	Biotin-d7; (+)-Biotin-d7; D-Biotin-d7; Vitamin B7-d7; Vitamin H-d7; Coenzyme R-d7; Hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanoic acid-d7; 5-[(3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoic acid-d7
EINECS	Contact for details

Quality Control

Our Fp-Biotin-D7 is manufactured under strict quality systems to ensure the highest isotopic and chemical purity required for sensitive analytical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing results from advanced analytical techniques including NMR, HPLC, and MS. We adhere to relevant industry standards for reference materials, and custom synthesis to meet specific purity or isotopic enrichment requirements is available.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Deuterium Enrichment)	≥ 98 atom % D
Chemical Purity (NMR)	Conforms
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.