Description

B-(2-Methyl-4-Thiazolyl)Boronic Acid is a high-purity organoboron building block, specifically a heterocyclic boronic acid derivative, essential for modern synthetic chemistry. Its core value lies in enabling efficient carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone methodology for constructing complex molecules. This compound is critically needed by research and development chemists in the pharmaceutical, agrochemical, and advanced materials industries for the synthesis of novel thiazole-containing compounds.

Application

• Pharmaceutical Intermediate: A key synthon for constructing active pharmaceutical ingredients (APIs) and drug candidates containing the 2-methylthiazole moiety.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides with tailored biological activity.
• Material Science Research: Serves as a building block for creating organic electronic materials, ligands for catalysts, and functional polymers.
• Suzuki-Miyaura Cross-Coupling: Primarily employed as a boronic acid coupling partner with aryl/heteroaryl halides or triflates to form biaryl linkages.
• Chemical Biology & Medicinal Chemistry: Facilitates the rapid generation of diverse compound libraries for high-throughput screening and structure-activity relationship (SAR) studies.
• Ligand Synthesis: Useful for preparing novel bidentate or polydentate ligands containing nitrogen and sulfur donor atoms for coordination chemistry.

Basic Information

Product Name	B-(2-Methyl-4-Thiazolyl)Boronic Acid
CAS No.	1246761-85-2
Molecular Formula	C4H6BNO2S
Molecular Weight	142.97 g/mol
Synonyms	(2-Methyl-1,3-thiazol-4-yl)boronic acid; (2-Methyl-4-thiazolyl)boronic Acid; 2-Methyl-4-thiazoleboronic acid; 4-Borono-2-methylthiazole; B-(2-Methyl-4-thiazolyl)boronic acid; 2-Methylthiazole-4-boronic acid; 1246761-85-2
EINECS	Contact for details

Quality Control

Our B-(2-Methyl-4-Thiazolyl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay (NMR)	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.