Description

(1-Phenylpiperidin-2-Yl)Methanol is a versatile chiral piperidine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its structural motif, which is integral to the development of pharmacologically active compounds, particularly in central nervous system (CNS) research. This high-purity intermediate is essential for pharmaceutical R&D teams and fine chemical manufacturers engaged in creating new therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for neurological targets.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• Asymmetric Synthesis: Employed as a chiral auxiliary or ligand precursor in catalytic asymmetric reactions to induce stereoselectivity.
• Chemical Research: Serves as a versatile scaffold for constructing complex nitrogen-containing heterocycles in academic and industrial laboratories.
• Reference Standard: Utilized as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Item	Details
Product Name	(1-Phenylpiperidin-2-Yl)Methanol
CAS No.	1246743-90-7
Molecular Formula	C12H17NO
Molecular Weight	191.27 g/mol
Synonyms	2-(Hydroxymethyl)-1-phenylpiperidine; 1-Phenyl-2-piperidinemethanol; α-(Hydroxymethyl)-1-phenylpiperidine; (1-Phenyl-2-piperidyl)methanol; 1-Phenyl-2-(hydroxymethyl)piperidine; (2-Piperidyl)phenylmethanol; 1-Phenylpiperidine-2-methanol
EINECS	Contact for details

Quality Control

Our (1-Phenylpiperidin-2-Yl)Methanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for pharmaceutical research. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.