Description

2-(Cyclohexylmethylamino)Pyridine-5-Boronic Acid is a specialized boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its primary value lies in its role as a key coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. This high-purity intermediate is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex molecules in the research and development of new drug candidates, especially those containing pyridine and biaryl motifs.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides that require specific, sterically defined boronic acid components.
• Material Science Research: Serves as a monomer or functionalization agent in the synthesis of organic electronic materials, such as polymers for OLEDs or conductive films.
• Ligand Precursor: Can be utilized to develop novel bidentate or tridentate ligands for catalysis in asymmetric synthesis and other transition metal-catalyzed processes.
• Chemical Biology Probes: Employed in the synthesis of molecular probes and tags for studying biological systems and protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-(Cyclohexylmethylamino)Pyridine-5-Boronic Acid
CAS No.	1246743-82-7
Molecular Formula	C₁₂H₁₉BN₂O₂
Molecular Weight	234.11 g/mol
Synonyms	5-Borono-2-[(cyclohexylmethyl)amino]pyridine; 2-[(Cyclohexylmethyl)amino]-5-pyridineboronic acid; (6-[(Cyclohexylmethyl)amino]pyridin-3-yl)boronic acid; 2-(Cyclohexylmethylamino)-5-pyridinylboronic Acid; 2-(Cyclohexylmethylamino)pyridin-5-ylboronic acid; B-[6-[(Cyclohexylmethyl)amino]-3-pyridinyl]boronic acid
EINECS	Contact for details

Quality Control

Our 2-(Cyclohexylmethylamino)Pyridine-5-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (argon or nitrogen) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.