Description

2-(2-Bromothiazol-5-Yl)Acetonitrile is a high-value brominated thiazole derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both a reactive bromine atom and a versatile nitrile group, makes it indispensable for constructing complex heterocyclic frameworks. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where it is used to introduce the 2-bromothiazole moiety into target molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors, antiviral agents, and anti-inflammatory compounds.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the thiazole ring system is a common bioactive scaffold.
• Material Science: Serves as a precursor for functionalized polymers and liquid crystals, leveraging its ability to undergo further cross-coupling and cyclization reactions.
• Chemical Synthesis: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic substitution reactions to create diverse thiazole-containing libraries for screening.

Basic Information

Product Name	2-(2-Bromothiazol-5-Yl)Acetonitrile
CAS No.	1246554-99-3
Molecular Formula	C5H3BrN2S
Molecular Weight	202.06 g/mol
Synonyms	2-(2-Bromo-1,3-thiazol-5-yl)acetonitrile; (2-Bromothiazol-5-yl)acetonitrile; 5-(Cyanomethyl)-2-bromothiazole; Acetonitrile, 2-(2-bromo-5-thiazolyl)-; 2-Bromo-5-thiazoleacetonitrile; 2-Bromothiazole-5-acetonitrile
EINECS	Contact for details

Quality Control

Our 2-(2-Bromothiazol-5-Yl)Acetonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our commitment to supply chain integrity and documentation transparency supports your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided to maintain product stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.