Description

(R)-(6-Bromo-Indan-1-Yl)-Carbamic Acid tert-Butyl Ester is a high-purity, chiral organic intermediate of significant importance in modern pharmaceutical synthesis. Its value lies in its role as a key building block for constructing complex, biologically active molecules with defined stereochemistry. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the research and development of novel therapeutic agents.
• API Synthesis: Used as a key building block in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs).
• Asymmetric Synthesis: Employed in stereoselective reactions to introduce the (R)-configured indane scaffold into target molecules.
• Medicinal Chemistry Research: Serves as a versatile starting material for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Preclinical Development: Used in the synthesis of compounds for pharmacological evaluation and toxicology studies.
• Process Chemistry: Investigated for scalable synthetic routes in the pilot-scale and commercial manufacturing of chiral drugs.

Basic Information

Product Name	(R)-(6-Bromo-Indan-1-Yl)-Carbamic Acid tert-Butyl Ester
CAS No.	1246509-78-3
Molecular Formula	C14H18BrNO2
Molecular Weight	312.20 g/mol
Synonyms	(R)-N-Boc-6-Bromo-1-aminoindane; (R)-tert-Butyl (6-bromo-2,3-dihydro-1H-inden-1-yl)carbamate; (R)-6-Bromo-1-indanylamine N-BOC; (R)-N-(tert-Butoxycarbonyl)-6-bromo-1-aminoindane; (R)-Boc-6-Bromo-1-aminoindane; (1R)-6-Bromo-2,3-dihydro-1H-inden-1-amine, N-[(1,1-dimethylethoxy)carbonyl]-; (R)-1-((tert-Butoxycarbonyl)amino)-6-bromoindane
EINECS	Contact for details

Quality Control

Our (R)-(6-Bromo-Indan-1-Yl)-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric purity and standard spectroscopic methods for identity confirmation, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.