Description

n-Boc-3-Bromo-6-Nitroindole is a high-purity, multi-functional indole derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of protecting, halogen, and nitro groups, enabling precise and complex molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active pharmaceutical ingredients (APIs) and complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex indole-based drug candidates, including kinase inhibitors and receptor modulators.
• Agrochemical Research: Used in the development of new herbicides and pesticides that leverage the indole scaffold for biological activity.
• Material Science: Serves as a monomer or functional unit in the creation of specialized polymers and organic electronic materials.
• Academic & R&D: A versatile reagent for methodological studies in cross-coupling reactions, such as Suzuki and Buchwald-Hartwig amination.
• Peptidomimetics: Employed in the design and synthesis of peptide analogs where the indole core mimics natural amino acid side chains.
• Fluorescent Probe Synthesis: Utilized as a starting material for constructing nitro- and bromo-substituted fluorophores for sensing applications.

Basic Information

Product Name	n-Boc-3-Bromo-6-Nitroindole
CAS No.	1246471-29-3
Molecular Formula	C₁₃H₁₃BrN₂O₄
Molecular Weight	341.16 g/mol
Synonyms	1-Boc-3-bromo-6-nitroindole; tert-Butyl 3-bromo-6-nitro-1H-indole-1-carboxylate; 3-Bromo-6-nitro-1H-indole-1-carboxylic acid tert-butyl ester; 3-Bromo-6-nitroindole-1-carboxylic acid tert-butyl ester; N-Boc-3-bromo-6-nitroindole; Boc-3-Br-6-NO₂-indole; 1-(tert-Butoxycarbonyl)-3-bromo-6-nitroindole
EINECS	Contact for details

Quality Control

Our n-Boc-3-Bromo-6-Nitroindole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is light-sensitive (store away from light). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.