Description

D-Erythro-Sphingosine-D7 is a high-purity, deuterium-labeled analog of the fundamental sphingolipid backbone, D-erythro-sphingosine. This stable isotope-labeled compound is essential for precise quantitative analysis in lipidomics research, enabling accurate tracing and measurement of sphingolipid metabolism and signaling pathways. It is a critical tool for researchers and analytical laboratories in the pharmaceutical, biotechnology, and life science sectors who require reliable internal standards for mass spectrometry.

Application

• Internal Standard for Mass Spectrometry (MS): Primary use as a quantitative reference standard in LC-MS/MS and GC-MS analysis of sphingolipids.
• Metabolic Pathway Tracing: Enables detailed studies of sphingolipid biosynthesis, turnover, and catabolism in cellular and in vivo models.
• Biomarker Discovery & Validation: Facilitates the accurate quantification of sphingosine and related metabolites in biological samples for disease research.
• Drug Development & Pharmacokinetics: Used to study the effects of drug candidates on sphingolipid metabolism and for bioanalytical method development.
• Clinical Research: Supports investigations into the role of sphingolipids in cancer, neurodegenerative diseases, and metabolic disorders.
• Quality Control in Diagnostics: Serves as a calibrant in diagnostic assays targeting sphingolipid pathways.

Basic Information

Product Name	D-Erythro-Sphingosine-D7
CAS No.	1246304-34-6
Molecular Formula	C18H30D7NO2
Molecular Weight	307.53 g/mol (approximate)
Synonyms	(2S,3R,4E)-2-Amino-4-octadecene-1,3-diol-D7; D-erythro-Sphingosine (2S,3R,4E-18:1) D7; Sphingosine-d7; Sphing-4-enine-d7; (2S,3R,4E)-2-Amino-4-octadecene-1,3-diol (phenyl-13C6, 3,4,5-2H3); Deuterated Sphingosine; Lipid Internal Standard D7; Stable Isotope-Labeled Sphingosine
EINECS	Contact for details

Quality Control

Every batch of D-Erythro-Sphingosine-D7 is manufactured and analyzed under strict quality systems to ensure the highest standards of isotopic purity and chemical identity required for sensitive analytical applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) providing detailed results for isotopic enrichment, chemical purity, and identity are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 98 atom % D
Chemical Purity (Titration)	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.