Description

(2-Carboxyethyl)Dimethyl-D6-Sulfonium Chloride is a high-purity, deuterium-labeled sulfonium salt used as a critical reagent in advanced chemical synthesis and analytical applications. Its primary value lies in its role as a stable isotope-labeled internal standard, enabling precise quantification and metabolic pathway tracing in complex matrices. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and analytical chemistry sectors who require high-fidelity tools for method development, quality control, and regulatory compliance.

Application

• Internal Standard for LC-MS/MS: Serves as a deuterated internal standard for the accurate quantification of related sulfonium compounds or metabolites in bioanalytical methods, enhancing data reliability for pharmacokinetic and toxicokinetic studies.
• Metabolic Pathway Research: Used as a tracer in drug metabolism and disposition studies to elucidate metabolic pathways and identify metabolites using mass spectrometry.
• Pharmaceutical Intermediate: Acts as a specialized building block or precursor in the synthesis of novel drug candidates, particularly where isotopic labeling is required for tracking or property modification.
• Analytical Reference Standard: Provides a certified reference material for method validation, calibration, and quality assurance in analytical laboratories to ensure regulatory compliance (e.g., FDA, EMA).
• Chemical Biology Probes: Utilized in the development of chemical probes for studying enzyme mechanisms or protein interactions where a sulfonium moiety is involved.
• Isotope Dilution Mass Spectrometry (IDMS): A key component in high-precision IDMS protocols for the absolute quantification of target analytes in environmental or clinical samples.

Basic Information

Item	Details
Product Name	(2-Carboxyethyl)Dimethyl-D6-Sulfonium Chloride
CAS No.	1246274-70-3
Molecular Formula	C5H5D6ClO2S
Molecular Weight	176.69 g/mol
Synonyms	3-(Dimethyl-d6-sulfonio)propanoate Chloride; (3-Carboxypropyl)dimethyl-d6-sulfonium Chloride; β-Carboxyethyldimethyl-d6-sulfonium Chloride; Deuterated S-Adenosylmethionine (SAM) Analog Precursor; D6-Dimethylsulfoniopropionate Chloride; DMSP-d6 Chloride; (2-Carboxyethyl)dimethylsulfonium-d6 Chloride
EINECS	Contact for details

Quality Control

Every batch of (2-Carboxyethyl)Dimethyl-D6-Sulfonium Chloride is manufactured and tested under strict quality management systems. We guarantee high chemical and isotopic purity through comprehensive analytical techniques including NMR, HPLC, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting batch-specific data for identity, purity (assay), isotopic enrichment, and impurities. Our quality commitment ensures the material meets the stringent requirements for use as a reference standard in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. For long-term storage, consider storing at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (MS)	≥ 99.0 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.