Description

5-Chloro-6-Iodo-1H-Pyrrolo[2,3-B]Pyridine is a high-value halogenated heterocyclic building block, specifically designed for advanced pharmaceutical and agrochemical research and development. Its unique pyrrolopyridine core, functionalized with chlorine and iodine atoms, makes it a critical intermediate for constructing complex molecules through cross-coupling reactions and further functionalization. This compound is essential for medicinal chemists and R&D professionals in the pharmaceutical, agrochemical, and material science industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel kinase inhibitors, anticancer agents, and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science Precursor: Serves as a building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes for studying biological pathways and protein functions.
• Cross-Coupling Reactions: The iodine and chlorine substituents provide orthogonal reactivity for sequential Suzuki, Sonogashira, and Buchwald-Hartwig amination reactions.
• Library Synthesis: A valuable scaffold for generating diverse compound libraries in high-throughput screening and drug discovery programs.

Basic Information

Product Name	5-Chloro-6-Iodo-1H-Pyrrolo[2,3-B]Pyridine
CAS No.	1246088-68-5
Molecular Formula	C7H4ClIN2
Molecular Weight	278.48 g/mol
Synonyms	5-Chloro-6-iodo-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 5-chloro-6-iodo-; 6-Iodo-5-chloro-1H-pyrrolo[2,3-b]pyridine; 5-Chloro-6-iodopyrrolo[2,3-b]pyridine; 5-Chloro-6-iodo-7-azaindole; 5-Chloro-6-iodo-1H-7-azaindole
EINECS	Contact for details

Quality Control

Our 5-Chloro-6-Iodo-1H-Pyrrolo[2,3-B]Pyridine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding R&D applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable and can support development projects requiring regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat and incompatible materials. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.