Description

(5-Amino-3-Methylthiophen-2-Yl)(4-Chlorophenyl)Methanone is a high-purity, specialized organic building block with the CAS number 1245807-18-4. This compound is a key intermediate valued for its unique molecular architecture, which combines a functionalized thiophene ring with a chlorinated benzophenone moiety. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A critical building block in the research and synthesis of new drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Serves as a precursor in the development of next-generation herbicides, fungicides, and insecticides, leveraging its heterocyclic structure.
• Material Science: Used in the creation of advanced organic electronic materials, such as organic semiconductors and conductive polymers.
• Chemical Synthesis: Functions as a versatile synthon for constructing complex heterocyclic compounds in academic and industrial research laboratories.
• Dye & Pigment Intermediate: Employed in the development of specialized dyes and pigments due to its chromophoric properties.

Basic Information

Product Name	(5-Amino-3-Methylthiophen-2-Yl)(4-Chlorophenyl)Methanone
CAS No.	1245807-18-4
Molecular Formula	C12H10ClNOS
Molecular Weight	251.73 g/mol
Synonyms	4-Chlorophenyl(5-amino-3-methyl-2-thienyl)methanone; 1-(4-Chlorophenyl)-2-(5-amino-3-methyl-2-thienyl)ethanone (common misnomer); 5-Amino-3-methyl-2-(4-chlorobenzoyl)thiophene; (5-Amino-3-methylthiophen-2-yl)(4-chlorophenyl)methanone; 4'-Chloro-5-amino-3-methyl-2-thienyl phenyl ketone; 2-(4-Chlorobenzoyl)-5-amino-3-methylthiophene; CAS 1245807-18-4
EINECS	Contact for details

Quality Control

Our (5-Amino-3-Methylthiophen-2-Yl)(4-Chlorophenyl)Methanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP and ISO 9001 guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and propensity for oxidation, prolonged exposure to light and air should be avoided. For long-term storage, consider an inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.