Description

3-Bromo-5-(Bromomethyl)-1H-Indole is a high-value, multi-functional brominated indole derivative. This compound serves as a critical advanced pharmaceutical intermediate (API) and versatile building block in organic synthesis, enabling the construction of complex molecular architectures. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing novel active compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potent kinase inhibitors, receptor antagonists, and other biologically active molecules targeting various disease pathways.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Material Science: Used in the creation of specialized organic electronic materials, including OLEDs and conductive polymers, due to its indole core and bromine functionality.
• Chemical Biology & Proteomics: Employed as a molecular probe or linker in activity-based protein profiling (ABPP) and bioconjugation strategies.
• Organic Synthesis: The bromine atoms provide excellent handles for further functionalization via cross-coupling reactions (e.g., Suzuki, Sonogashira) and nucleophilic substitutions, enabling rapid diversification.

Basic Information

Product Name	3-Bromo-5-(Bromomethyl)-1H-Indole
CAS No.	1245649-27-7
Molecular Formula	C9H7Br2N
Molecular Weight	288.97 g/mol
Synonyms	5-(Bromomethyl)-3-bromo-1H-indole; 3,5-Dibromo-1H-indole-5-methanol (bromomethyl derivative); 1H-Indole, 3-bromo-5-(bromomethyl)-; 3-Bromo-5-bromomethylindole; BBMI
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for all our fine chemical intermediates. Each batch of 3-Bromo-5-(Bromomethyl)-1H-Indole is analyzed using advanced techniques including HPLC, GC-MS, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment. Our quality system supports compliance with cGMP and ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.