Description

Methyl 5-Cyano-1H-Indole-2-Carboxylate CAS NO 1245648-71-8 is a high-value, functionalized indole derivative serving as a critical building block in advanced organic synthesis. Its molecular architecture, featuring both cyano and ester functional groups, makes it an indispensable precursor for constructing complex heterocyclic frameworks. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of potent kinase inhibitors, receptor antagonists, and other biologically active indole-based compounds.
• Agrochemical Research: Used in developing new generations of herbicides, fungicides, and plant growth regulators that leverage the indole scaffold.
• Material Science: Serves as a precursor for organic semiconductors, light-emitting diodes (OLEDs), and other electronic materials due to its conjugated system.
• Chemical Biology: Employed as a probe or labeling agent in biochemical research and assay development.
• Academic & Contract Research: Utilized in methodological development and discovery chemistry within university and CRO laboratories.
• Dye & Pigment Industry: Acts as an intermediate for synthesizing specialized indole-based dyes and colorants.

Basic Information

Product Name	Methyl 5-Cyano-1H-Indole-2-Carboxylate
CAS No.	1245648-71-8
Molecular Formula	C11H8N2O2
Molecular Weight	200.19 g/mol
Synonyms	Methyl 5-cyanoindole-2-carboxylate; 1H-Indole-2-carboxylic acid, 5-cyano-, methyl ester; 5-Cyano-1H-indole-2-carboxylic acid methyl ester; 2-Carbomethoxy-5-cyanoindole; Methyl 5-cyano-1H-indole-2-carboxylate; 1245648-71-8
EINECS	Contact for details

Quality Control

Every batch of Methyl 5-Cyano-1H-Indole-2-Carboxylate is manufactured under strict quality management protocols. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, confirming compliance with customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.