Description

tert-Butyl 2-Bromothiazol-4-Ylcarbamate is a high-purity, advanced pharmaceutical intermediate characterized by its bromothiazole core and carbamate protecting group. This compound is a critical building block in modern medicinal chemistry, enabling the synthesis of complex molecules with targeted biological activity. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of potential drug candidates, especially those containing functionalized thiazole rings.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and library synthesis for hit-to-lead optimization in drug discovery programs.
• Agrochemical Development: Serves as a precursor in the research and synthesis of new crop protection agents and pesticides.
• Chemical Biology Probes: Utilized for the design and construction of molecular probes to study biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds under cGMP conditions.

Basic Information

Product Name	tert-Butyl 2-Bromothiazol-4-Ylcarbamate
CAS No.	1245647-95-3
Molecular Formula	C8H11BrN2O2S
Molecular Weight	279.15 g/mol
Synonyms	2-Bromo-4-(((tert-butoxycarbonyl)amino)thiazole; 4-(((tert-Butoxycarbonyl)amino)-2-bromothiazole; tert-Butyl N-(2-bromothiazol-4-yl)carbamate; 2-Bromothiazol-4-yl-carbamic acid tert-butyl ester; BOC-2-Bromo-4-aminothiazole; (2-Bromo-1,3-thiazol-4-yl)carbamic acid 1,1-dimethylethyl ester; tert-Butyl (2-bromo-1,3-thiazol-4-yl)carbamate
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-Bromothiazol-4-Ylcarbamate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research and development applications. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed results from HPLC, NMR, and mass spectrometry. Our quality system is designed to support regulatory filings and meets the stringent standards required for pharmaceutical intermediate supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is light-sensitive (store away from light). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.