Description

tert-Butyl 5-Bromo-3-Ethyl-1H-indazole-1-carboxylate is a high-purity, advanced pharmaceutical intermediate crucial for modern drug discovery and development. Its value lies in its role as a versatile building block for synthesizing complex bioactive molecules, particularly in medicinal chemistry. This compound is primarily needed by R&D laboratories and production facilities in the pharmaceutical, biotechnology, and fine chemical sectors.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially for oncology and central nervous system (CNS) targeted therapies.
• Medicinal Chemistry Research: Used extensively in hit-to-lead optimization and structure-activity relationship (SAR) studies to develop new drug candidates.
• Organic Synthesis Building Block: The bromo and protected indazole functionalities allow for further functionalization via cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig).
• Agrochemical Development: Potential application in the research and synthesis of new crop protection agents and pesticides.
• Material Science Research: Can be utilized in the development of specialty polymers or organic electronic materials due to its heterocyclic structure.

Basic Information

Product Name	tert-Butyl 5-Bromo-3-Ethyl-1H-indazole-1-carboxylate
CAS No.	1245646-78-9
Molecular Formula	C14H17BrN2O2
Molecular Weight	325.20 g/mol
Synonyms	5-Bromo-3-ethyl-1H-indazole-1-carboxylic acid tert-butyl ester; 1-Boc-5-bromo-3-ethylindazole; tert-Butyl 5-bromo-3-ethyl-1H-indazole-1-carboxylate; 5-Bromo-3-ethyl-1-((tert-butoxy)carbonyl)-1H-indazole; 1H-Indazole-1-carboxylic acid, 5-bromo-3-ethyl-, 1,1-dimethylethyl ester; 5-Bromo-3-ethylindazole-1-carboxylic acid tert-butyl ester; Boc-5-bromo-3-ethylindazole
EINECS	Contact for details

Quality Control

Our tert-Butyl 5-Bromo-3-Ethyl-1H-indazole-1-carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.