Description

1-Chloro-6-Methylisoquinoline-5-Carboxylicacid is a high-purity, synthetically versatile heterocyclic building block essential for advanced organic synthesis. Its unique molecular scaffold makes it a critical intermediate for developing novel active pharmaceutical ingredients (APIs) and specialty fine chemicals. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting neurological disorders and oncology.
• Agrochemical Research: Used as a building block for developing new generation herbicides and fungicides with novel modes of action.
• Ligand Synthesis: Serves as a starting material for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the research and development of organic electronic materials and advanced polymers.
• Chemical Biology Probes: Utilized to create isoform-selective enzyme inhibitors and other molecular probes for biological research.
• Custom Synthesis: A fundamental substrate for contract research organizations (CROs) and CDMOs performing bespoke synthetic routes for clients.

Basic Information

Product Name	1-Chloro-6-Methylisoquinoline-5-Carboxylicacid
CAS No.	1245643-02-0
Molecular Formula	C11H8ClNO2
Molecular Weight	221.64 g/mol
Synonyms	5-Carboxy-1-chloro-6-methylisoquinoline; 1-Chloro-6-methyl-5-isoquinolinecarboxylic acid; 1-Chloro-6-methylisoquinoline-5-carboxylic acid; 6-Methyl-1-chloroisoquinoline-5-carboxylic acid; 1245643-02-0; 1-Chloro-6-methyl-5-isoquinoline carboxylic acid; 1-Chloro-6-methylisoquinoline-5-carboxylate
EINECS	Contact for details

Quality Control

Our 1-Chloro-6-Methylisoquinoline-5-Carboxylicacid is manufactured under strict quality management systems to ensure batch-to-batch consistency and reliability for your critical syntheses. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is supplied with every shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.