Description

Oleoyl Ethanolamide-D2 CAS NO 1245477-09-1 is a deuterated analog of oleoylethanolamide (OEA), a bioactive lipid mediator. This compound is of significant interest for its utility as an internal standard in quantitative mass spectrometry, enabling precise pharmacokinetic and metabolic studies. It is primarily sought by researchers and manufacturers in the pharmaceutical, biotechnology, and analytical chemistry sectors for drug discovery and development workflows.

Application

• Internal Standard for LC-MS/MS: Used for the accurate quantification of endogenous oleoylethanolamide in biological matrices like plasma, serum, and tissue homogenates.
• Metabolic Pathway Research: A critical tool for tracing and studying the metabolism and pharmacokinetics of OEA and related N-acylethanolamines.
• Pharmaceutical R&D: Supports drug development programs targeting the endocannabinoid system, appetite regulation, and lipid signaling pathways.
• Biomarker Analysis: Enables reliable measurement of OEA as a potential biomarker in clinical and preclinical studies related to metabolic disorders.
• Reference Material: Serves as a high-purity certified reference material (CRM) for analytical method development and validation.
• Isotope Dilution Assays: Essential for isotope dilution techniques to ensure maximum accuracy and precision in bioanalytical measurements.

Basic Information

Product Name	Oleoyl Ethanolamide-D2
CAS No.	1245477-09-1
Molecular Formula	C20H37D2NO2
Molecular Weight	327.53 g/mol (approx.)
Synonyms	N-(2-Hydroxyethyl)-9Z-octadecenamide-d2; Oleoylethanolamide-d2; OEA-d2; (9Z)-N-(2-Hydroxyethyl)octadec-9-enamide-d2; Deuterated Oleoylethanolamide; N-Oleoylethanolamine-d2; 9-Octadecenamide, N-(2-hydroxyethyl)-, (9Z)-, deuterated
EINECS	Contact for details

Quality Control

Our Oleoyl Ethanolamide-D2 is manufactured under strict quality management systems. Each batch is characterized and tested to ensure high isotopic purity and chemical identity, meeting the exacting requirements for analytical reference standards. A comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (D, %), chemical purity (by HPLC), and structural confirmation (by NMR/MS) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. This material is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR & MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D)	≥ 98 atom % D
Isotopic Enrichment	≥ 99% (D2)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.