Description

6-Bromo-1-Tosyl-1H-Indazole-4-Carbonitrile is a high-value, multi-functional heterocyclic building block used in advanced organic synthesis. This compound is critical for medicinal chemistry research and development, serving as a key precursor for constructing complex molecular architectures. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and other biologically active compounds.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probe Development: Serves as a scaffold for creating molecular probes to study biological pathways and protein functions.
• Agrochemical Synthesis: Potential intermediate in the development of new crop protection agents and pesticides.
• Material Science Research: Investigated as a precursor for advanced organic electronic materials and functional polymers.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects.

Basic Information

Product Name	6-Bromo-1-Tosyl-1H-Indazole-4-Carbonitrile
CAS No.	1245464-56-5
Molecular Formula	C15H10BrN3O2S
Molecular Weight	376.23 g/mol
Synonyms	6-Bromo-1-(4-methylphenyl)sulfonyl-1H-indazole-4-carbonitrile; 1H-Indazole-4-carbonitrile, 6-bromo-1-[(4-methylphenyl)sulfonyl]-; 6-Bromo-1-tosylindazole-4-carbonitrile; 6-Bromo-1-(p-tolylsulfonyl)-1H-indazole-4-carbonitrile; 1245464-56-5; BTIC; 6-Br-1-Ts-indazole-4-CN
EINECS	Contact for details

Quality Control

We supply 6-Bromo-1-Tosyl-1H-Indazole-4-Carbonitrile in high-purity grades suitable for research and development. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and MS are available upon request. We adhere to a strict quality management system to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under inert atmosphere for long-term storage to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.