Description

Ethyl 5-Chloro-1-(2-Fluorophenyl)-1H-Pyrazole-4-Carboxylate is a high-purity, synthetically valuable pyrazole derivative, serving as a critical building block in advanced organic synthesis. Its molecular architecture, featuring both chloro and fluoro substituents, makes it an essential intermediate for constructing complex molecules with targeted biological activity. This compound is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Chemical Synthesis Building Block: Employed in organic synthesis for constructing complex pyrazole-containing scaffolds due to its reactive ester and halogen functional groups.
• Material Science Research: Investigated as a monomer or functional additive in the development of specialty polymers and advanced materials.
• Academic & Contract Research: Sourced by universities and CROs (Contract Research Organizations) for fundamental chemical research and custom synthesis projects.

Basic Information

Product Name	Ethyl 5-Chloro-1-(2-Fluorophenyl)-1H-Pyrazole-4-Carboxylate
CAS No.	1245279-25-7
Molecular Formula	C12H10ClFN2O2
Molecular Weight	268.67 g/mol
Synonyms	Ethyl 5-chloro-1-(2-fluorophenyl)-1H-pyrazole-4-carboxylate; 5-Chloro-1-(2-fluorophenyl)-1H-pyrazole-4-carboxylic acid ethyl ester; 1-(2-Fluorophenyl)-5-chloro-1H-pyrazole-4-carboxylic acid ethyl ester; 1245279-25-7; UNII-9J6I9V22Q4; 9J6I9V22Q4; SCHEMBL23306279; DTXSID90648686; AKOS025147064; A1-03449
EINECS	Contact for details

Quality Control

Our Ethyl 5-Chloro-1-(2-Fluorophenyl)-1H-Pyrazole-4-Carboxylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.