Description

2-Fluoro-3-Methylbenzenethiol (2-Fluoro-m-Tolyl Mercaptan) is a specialized organosulfur compound featuring a thiol (-SH) functional group on a fluorinated aromatic ring. This structure makes it a valuable building block for introducing sulfur and fluorine motifs into target molecules, which is critical for modulating the physicochemical and biological properties of advanced materials and pharmaceuticals. It is primarily sought by R&D chemists and process developers in the agrochemical and pharmaceutical industries for applications in catalysis, ligand synthesis, and as a key intermediate in the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly where fluorine and sulfur atoms are required for bioactivity or metabolic stability.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atom enhances lipophilicity and environmental persistence.
• Ligand and Catalyst Development: Acts as a precursor for creating specialized ligands in transition metal catalysis, useful in cross-coupling and other synthetic transformations.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic materials that require specific aromatic thiol components.
• Chemical Synthesis Building Block: Provides a versatile handle for nucleophilic aromatic substitution and other reactions to construct complex molecular architectures.

Basic Information

Product Name	2-Fluoro-3-Methylbenzenethiol
CAS No.	1243283-09-1
Molecular Formula	C7H7FS
Molecular Weight	142.19 g/mol
Synonyms	2-Fluoro-m-Tolyl Mercaptan; 2-Fluoro-3-Methylbenzenethiol; 3-Methyl-2-fluorobenzenethiol; 2-Fluoro-3-methylthiophenol; (2-Fluoro-3-methylphenyl)thiol; 2-Fluoro-3-toluenethiol; 2-Fluoro-3-methylbenzenethiol CAS 1243283-09-1
EINECS	Contact for details

Quality Control

Our production of 2-Fluoro-3-Methylbenzenethiol adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and scale-up applications. Each lot is characterized using advanced analytical techniques including GC, HPLC, and NMR. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Due to its thiol nature and sensitivity to oxidation, minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.