Description

2-Iodo-Indole-5-Carbonitrile is a high-purity, multi-functional indole derivative, serving as a critical building block in advanced organic synthesis. Its unique halogenated and nitrile-substituted structure makes it an indispensable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other biologically active heterocyclic compounds.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators due to its reactive halogen and nitrile functionalities.
• Material Science: Serves as a monomer or building block for creating specialized polymers and organic electronic materials.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Sonogashira) and as a versatile scaffold for constructing complex indole-based libraries in medicinal chemistry.
• Bioconjugation & Probe Development: The reactive iodine atom makes it suitable for radiolabeling or as a handle for attaching fluorescent tags in biochemical research.

Basic Information

Product Name	2-Iodo-Indole-5-Carbonitrile
CAS No.	1243279-26-6
Molecular Formula	C9H5IN2
Molecular Weight	284.06 g/mol
Synonyms	5-Cyano-2-iodo-1H-indole; 2-Iodo-1H-indole-5-carbonitrile; 1H-Indole-5-carbonitrile, 2-iodo-; 2-Iodoindole-5-carbonitrile; 1243279-26-6; 2-Iodo-5-cyanoindole; 5-Cyano-2-iodoindole
EINECS	Contact for details

Quality Control

Every batch of 2-Iodo-Indole-5-Carbonitrile is manufactured and tested under strict quality management protocols to ensure consistency and reliability for your research and production needs. Our products undergo rigorous quality testing, including HPLC, NMR, and mass spectrometry, to verify identity, purity, and conformity to specifications. Certificates of Analysis (COA) are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.