Description

(R)-2-Mercaptobutanoic Acid is a high-purity chiral building block and a key intermediate in the synthesis of optically active compounds. Its value lies in the unique reactivity of the thiol group and the stereochemical control provided by the (R)-configuration, enabling the production of enantiomerically pure pharmaceuticals and agrochemicals. This product is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate chiral sulfur-containing motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of drugs targeting cardiovascular, metabolic, and central nervous system disorders.
• Agrochemical Synthesis: Used in the production of enantiomerically pure herbicides, fungicides, and pesticides, where the specific stereochemistry can significantly influence biological activity and environmental safety.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis, facilitating reactions such as hydrogenation, epoxidation, and C-C bond formation.
• Peptide Mimetics and Bioconjugation: The thiol functionality allows for site-specific modification of peptides, proteins, and other biomolecules, useful in drug delivery systems and biochemical probes.
• Flavor and Fragrance Industry: Potential use as an intermediate for synthesizing chiral sulfur-containing flavor compounds, contributing to complex aroma profiles.
• Material Science Research: Employed in the development of novel polymers and functional materials with tailored properties derived from its chiral center and reactive groups.

Basic Information

Product Name	(R)-2-Mercaptobutanoic Acid
CAS No.	1242881-37-3
Molecular Formula	C4H8O2S
Molecular Weight	120.17 g/mol
Synonyms	(R)-2-Sulfanylbutanoic acid; (R)-2-Thiobutanoic acid; (R)-2-Mercaptobutyric acid; D-2-Mercaptobutanoic acid; (2R)-2-Sulfanylbutanoic acid; (R)-α-Mercaptobutyric acid; (R)-Butanoic acid, 2-mercapto-; (R)-2-Mercapto-butanoic acid
EINECS	Contact for details

Quality Control

Our (R)-2-Mercaptobutanoic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, enantiomeric excess, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and volatility. Keep the container in a cool, well-ventilated place, away from heat, sparks, and open flames. Due to its moisture-sensitive nature, the container should be sealed immediately after use.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.