Description

5-Methyl-4-Azaindole-2-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate belonging to the azaindole class of heterocyclic compounds. Its core value lies in its role as a critical building block for synthesizing novel, small-molecule drug candidates, particularly in oncology and antiviral research. This compound is essential for medicinal chemists and R&D teams in the pharmaceutical, biotechnology, and fine chemical industries who are developing next-generation therapeutics.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of protein kinase inhibitors and other targeted cancer therapies.
• Medicinal Chemistry R&D: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Research: Employed in the development of enzyme inhibitors and probes for studying cellular signaling pathways.
• Fine Chemical Synthesis: Acts as a specialized building block for creating complex heterocyclic molecules with potential biological activity.
• Contract Manufacturing (CMO/CDMO): Supplied to organizations engaged in the custom synthesis of Active Pharmaceutical Ingredients (APIs) for clinical trials.

Basic Information

Product Name	5-Methyl-4-Azaindole-2-Carboxylic Acid
CAS No.	1242427-62-8
Molecular Formula	C9H8N2O2
Molecular Weight	176.17 g/mol
Synonyms	5-Methyl-1H-pyrrolo[3,2-b]pyridine-2-carboxylic acid; 4-Aza-5-methylindole-2-carboxylic acid; 5-Methyl-4-aza-indole-2-carboxylic acid; 1H-Pyrrolo[3,2-b]pyridine-2-carboxylic acid, 5-methyl-; 5-Methyl-1H-pyrrolo[3,2-b]pyridin-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 5-Methyl-4-Azaindole-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.