Description

Bicyclo[2.2.1]Heptane-1-Methanesulfonic Acid, 7,7-Dimethyl-2-Oxo-, Ethyl Ester, (1R,4S)- is a high-purity, chiral building block of significant interest in advanced organic synthesis. Its unique, rigid bicyclic framework and defined stereochemistry make it a valuable precursor for constructing complex molecular architectures with precise spatial orientation. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Asymmetric Catalyst Ligand Precursor: Used to synthesize specialized ligands for metal-catalyzed reactions requiring high enantioselectivity.
• Agrochemical Synthesis: Serves as a building block for creating novel, stereochemically-defined pesticides and herbicides.
• Material Science Research: Employed in the development of advanced polymers and liquid crystals where the rigid norbornane skeleton imparts specific physical properties.
• Academic & R&D Laboratories: Utilized in methodological studies and the synthesis of complex natural product analogs.
• Fine Chemical Production: Integral to the multi-step synthesis of high-value, low-volume specialty chemicals.

Basic Information

Product Name	Bicyclo[2.2.1]Heptane-1-Methanesulfonic Acid, 7,7-Dimethyl-2-Oxo-, Ethyl Ester, (1R,4S)-
CAS No.	1242184-36-6
Molecular Formula	C12H20O4S
Molecular Weight	260.35 g/mol
Synonyms	(1R,4S)-1-[(Ethylsulfonyl)methyl]-7,7-dimethyl-2-oxobicyclo[2.2.1]heptane; (1R,4S)-Ethyl 7,7-dimethyl-2-oxobicyclo[2.2.1]heptane-1-methanesulfonate; endo-(1R,4S)-7,7-Dimethyl-2-oxobicyclo[2.2.1]heptane-1-methanesulfonic acid ethyl ester; (1R,4S)-7,7-Dimethyl-2-oxonorbornane-1-methanesulfonic Acid Ethyl Ester; endo-(1R,4S)-Norbornane Sulfonate Ester Derivative
EINECS	Contact for details

Quality Control

Our production of Bicyclo[2.2.1]Heptane-1-Methanesulfonic Acid, 7,7-Dimethyl-2-Oxo-, Ethyl Ester, (1R,4S)- adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical characterization, including chiral purity verification, to ensure it meets the exacting standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity (HPLC/GC), enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to preserve optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.