Description

6-Bromo-8-Fluoro-3,4-Dihydroisoquinolin-1(2H)-One is a high-value, multi-functional heterocyclic building block designed for advanced chemical synthesis. This compound is critical for medicinal chemistry research and pharmaceutical development, offering a versatile scaffold for creating novel active ingredients. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce specific halogenated motifs into complex molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Medicinal Chemistry Research: Used as a privileged scaffold for structure-activity relationship (SAR) studies and library synthesis due to its bromo and fluoro substituents, which are common in bioactive molecules.
• Agrochemical Development: Acts as a building block for creating novel herbicides, fungicides, and insecticides where the isoquinolinone core provides specific biological activity.
• Chemical Biology Probes: Employed in the development of molecular probes and tool compounds for studying enzyme function and biological pathways.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and advanced organic materials with unique electronic properties.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations offering custom synthesis and process development services for their global clientele.

Basic Information

Product Name	6-Bromo-8-Fluoro-3,4-Dihydroisoquinolin-1(2H)-One
CAS No.	1242157-15-8
Molecular Formula	C9H7BrFNO
Molecular Weight	244.06 g/mol
Synonyms	6-Bromo-8-fluoro-1,2,3,4-tetrahydroisoquinolin-1-one; 8-Fluoro-6-bromo-3,4-dihydro-1H-isoquinolin-1-one; 6-Bromo-8-fluoro-3,4-dihydro-1(2H)-isoquinolinone; 1(2H)-Isoquinolinone, 6-bromo-8-fluoro-3,4-dihydro-; 1242157-15-8; 6-Br-8-F-dihydroisoquinolinone
EINECS	Contact for details

Quality Control

Every batch of 6-Bromo-8-Fluoro-3,4-Dihydroisoquinolin-1(2H)-One is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our products are suitable for research and development applications, with specifications tailored to meet project-specific requirements. Certificates of Analysis (COA) documenting purity (typically by HPLC), identity (by NMR/IR), and impurity profiles are available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids, strong bases, and strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.