Description

2-(3-Chloro-2-(Hydroxymethyl)Phenyl)-6-Cyclopropyl-8-Fluoroisoquinolin-1(2H)-One is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active pharmaceutical ingredients (APIs). This compound matters for its role as a critical building block in modern medicinal chemistry, enabling the development of targeted therapies. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the discovery and production of new drugs, particularly in areas requiring complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for oncology and central nervous system (CNS) targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes in drug discovery.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core structural component in the multi-step synthesis of complex APIs.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up services for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	2-(3-Chloro-2-(Hydroxymethyl)Phenyl)-6-Cyclopropyl-8-Fluoroisoquinolin-1(2H)-One
CAS No.	1242156-55-3
Molecular Formula	C19H15ClFNO2
Molecular Weight	343.78 g/mol
Synonyms	6-Cyclopropyl-8-fluoro-2-[3-chloro-2-(hydroxymethyl)phenyl]-1(2H)-isoquinolinone; 2-(3-Chloro-2-(hydroxymethyl)phenyl)-6-cyclopropyl-8-fluoroisoquinolin-1(2H)-one; 1242156-55-3; 6-Cyclopropyl-8-fluoro-2-(3-chloro-2-(hydroxymethyl)phenyl)isoquinolin-1(2H)-one; Isoquinolin-1(2H)-one, 2-[3-chloro-2-(hydroxymethyl)phenyl]-6-cyclopropyl-8-fluoro-
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We implement strict in-process controls and final release testing, including identity confirmation, purity assay, and impurity profiling. Certificates of Analysis (COA) are available upon request, detailing batch-specific results. Our quality management system supports the stringent requirements of pharmaceutical development and manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to ensure maximum stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.