Description

2-Chloro-6-(6-Cyclopropyl-8-Fluoro-1-Oxoisoquinolin-2(1H)-Yl)Benzaldehyde is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant commercial value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. It is primarily sought after by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the development of next-generation small-molecule drugs.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of proprietary drug candidates, especially those targeting complex disease pathways.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Synthesis: Used in the final stages or key transformations during the manufacturing process of target active pharmaceutical ingredients.
• Chemical Reference Standard: Provides a high-purity benchmark for analytical method development, validation, and quality control in regulatory submissions.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial production scales.

Basic Information

Product Name	2-Chloro-6-(6-Cyclopropyl-8-Fluoro-1-Oxoisoquinolin-2(1H)-Yl)Benzaldehyde
CAS No.	1242156-54-2
Molecular Formula	C19H13ClFNO2
Molecular Weight	341.76 g/mol
Synonyms	2-Chloro-6-[(6-cyclopropyl-8-fluoro-1-oxo-1,2-dihydroisoquinolin-2-yl)]benzaldehyde; 2-Chloro-6-(6-cyclopropyl-8-fluoro-1-oxo-1,2-dihydroisoquinolin-2-yl)benzaldehyde; 1242156-54-2; Benzaldehyde, 2-chloro-6-(6-cyclopropyl-8-fluoro-1-oxo-1,2-dihydro-2-isoquinolinyl)-; 2-(2-Chloro-6-formylphenyl)-6-cyclopropyl-8-fluoro-1,2-dihydroisoquinolin-1-one
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-(6-Cyclopropyl-8-Fluoro-1-Oxoisoquinolin-2(1H)-Yl)Benzaldehyde is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical R&D and cGMP intermediate applications. Certificates of Analysis (COA) with detailed chromatographic data are provided and can be tailored to support regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). This material is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.