Description

2-Amino-6-(Trifluoromethyl)-1H-Indole-3-Carbonitrile is a high-value, multi-functional heterocyclic building block characterized by its indole core, amino, nitrile, and trifluoromethyl substituents. This compound matters for its critical role in modern medicinal chemistry and agrochemical research, where it serves as a versatile scaffold for constructing novel molecules with targeted biological activity. Pharmaceutical and agrochemical R&D teams need it for the development of new active ingredients, leveraging its unique structure to modulate properties like potency, metabolic stability, and lipophilicity.

Application

• Key synthetic intermediate in the research and development of new pharmaceutical candidates, particularly in oncology and CNS disorders.
• Advanced building block for constructing complex molecules in medicinal chemistry and combinatorial libraries for high-throughput screening.
• Precursor in the synthesis of agrochemicals, such as herbicides and fungicides, where the trifluoromethyl group enhances bioactivity.
• Versatile scaffold for material science research, particularly in the development of organic semiconductors and fluorescent dyes.
• Used in academic and industrial laboratories for method development and studying structure-activity relationships (SAR).

Basic Information

Product Name	2-Amino-6-(Trifluoromethyl)-1H-Indole-3-Carbonitrile
CAS No.	1242140-69-7
Molecular Formula	C10H6F3N3
Molecular Weight	225.17 g/mol
Synonyms	2-Amino-6-(trifluoromethyl)-1H-indole-3-carbonitrile; 6-(Trifluoromethyl)-1H-indole-2,3-diamine-3-carbonitrile; 2-Amino-6-trifluoromethylindole-3-carbonitrile; 1242140-69-7; 2-Amino-6-(trifluoromethyl)indole-3-carbonitrile; 3-Cyano-2-amino-6-(trifluoromethyl)indole; 6-Trifluoromethyl-2-aminoindole-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 2-Amino-6-(Trifluoromethyl)-1H-Indole-3-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect this light-sensitive compound from moisture and atmospheric degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.