Description

R-3,3'-Bis(1-Naphthyl)-5,5',6,6',7,7',8,8'-Octahydro-1,1'-Binaphthyl-2,2'-Diyl Hydrogenphosphate is a sophisticated chiral phosphoric acid derivative, serving as a high-performance organocatalyst and chiral ligand. Its value lies in enabling highly enantioselective transformations critical for the synthesis of complex, single-enantiomer molecules. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise stereochemical control.

Application

• Asymmetric Organocatalysis: A key catalyst for enantioselective reactions such as Friedel-Crafts alkylations, transfer hydrogenations, and Mannich-type reactions.
• Pharmaceutical Intermediate Synthesis: Used in the stereoselective construction of chiral active pharmaceutical ingredients (APIs) and key intermediates.
• Chiral Ligand in Metal Complexes: Can coordinate with metals to form complexes for asymmetric metal-catalyzed processes.
• Agrochemical Research: Employed in the development of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Facilitates the synthesis of specialty chemicals, flavors, and fragrances requiring high optical purity.
• Academic & Industrial R&D: A valuable tool for methodological development in synthetic organic chemistry laboratories.

Basic Information

Product Name	R-3,3'-Bis(1-Naphthyl)-5,5',6,6',7,7',8,8'-Octahydro-1,1'-Binaphthyl-2,2'-Diyl Hydrogenphosphate
CAS No.	1242066-20-1
Molecular Formula	C44H35O4P
Molecular Weight	658.72 g/mol
Synonyms	(R)-3,3'-Bis(1-naphthyl)-1,1'-binaphthyl-2,2'-diyl hydrogenphosphate; (R)-3,3'-Bis(1-naphthyl)-5,5',6,6',7,7',8,8'-octahydro-BINOL phosphate; (R)-3,3'-Di(1-naphthyl)-H8-BINOL phosphoric acid; R-3,3'-Di-1-naphthyl-H8-BINAP acid phosphate; (R)-H8-BINOL-3,3'-di(1-naphthyl) phosphate; Chiral phosphoric acid catalyst derivative; (R)-TRIP analog (H8); Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our production of R-3,3'-Bis(1-Naphthyl)-5,5',6,6',7,7',8,8'-Octahydro-1,1'-Binaphthyl-2,2'-Diyl Hydrogenphosphate adheres to stringent internal quality standards to ensure batch-to-batch consistency and high enantiomeric excess (ee). Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and identity. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under an inert atmosphere when appropriate for prolonged manipulations to ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.