Description

6-Chloro-2-Piperidin-4-Yl-1H-Benzimidazole Dihydrochloride is a high-purity, advanced pharmaceutical intermediate and research chemical. This compound is valued for its role as a key building block in the synthesis of novel bioactive molecules, particularly in medicinal chemistry research. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Kinase Inhibitor Development: Serves as a key structural component in the research and development of novel kinase inhibitors.
• Biochemical Tool Compound: Employed in biochemical assays and as a reference standard in pharmacological studies.
• Organic Synthesis Building Block: Utilized in multi-step synthetic routes for constructing complex heterocyclic compounds.

Basic Information

Product Name	6-Chloro-2-Piperidin-4-Yl-1H-Benzimidazole Dihydrochloride
CAS No.	1241675-83-1
Molecular Formula	C₁₂H₁₅ClN₃·2HCl
Molecular Weight	308.64 g/mol (Free base: 236.72 g/mol)
Synonyms	6-Chloro-2-(4-piperidinyl)-1H-benzimidazole dihydrochloride; 2-(4-Piperidinyl)-6-chloro-1H-benzimidazole dihydrochloride; 6-Chloro-2-piperidin-4-yl-1H-benzo[d]imidazole dihydrochloride; 1241675-83-1; UNII-9V6H9FZU1C; 9V6H9FZU1C; Benzimidazole, 6-chloro-2-(4-piperidinyl)-, dihydrochloride
EINECS	Contact for details

Quality Control

Our 6-Chloro-2-Piperidin-4-Yl-1H-Benzimidazole Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting its use in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.