Description

3-Azabicyclo[3.2.1]Octane-8-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate featuring a unique bridged bicyclic structure. This compound is of significant commercial interest for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of complex small-molecule therapeutics, particularly within the central nervous system (CNS) and metabolic disease domains.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel therapeutic targets.
• API Synthesis: Serves as a core scaffold in the multi-step synthesis of complex, high-value active pharmaceutical ingredients.
• Chemical Biology: Employed as a molecular probe or ligand in the study of biological pathways and enzyme inhibition.
• Custom Synthesis: A starting material for the contract manufacturing of specialized fine chemicals and bespoke organic compounds.

Basic Information

Product Name	3-Azabicyclo[3.2.1]Octane-8-Carboxylic Acid
CAS No.	1240562-11-1
Molecular Formula	C8H13NO2
Molecular Weight	155.19 g/mol
Synonyms	8-Carboxy-3-azabicyclo[3.2.1]octane; 3-Azabicyclo[3.2.1]octane-8-carboxylic acid; 8-Carboxy-3-azanorbornane; 3-Azanorbornane-8-carboxylic acid; (1R,5S)-3-Azabicyclo[3.2.1]octane-8-carboxylic acid (for specific stereoisomer); 8-Carboxy-3-azabicyclo[3.2.1]octane hydrochloride (salt form); Bicyclic proline derivative
EINECS	Contact for details

Quality Control

Our 3-Azabicyclo[3.2.1]Octane-8-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the exacting standards required for pharmaceutical R&D and cGMP applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. The container should be kept tightly sealed in a desiccator to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.