Description

1-Methyl-2,3-Dihydro-1H-Indol-5-Ylamine Dihydrochloride is a high-purity, synthetically derived organic salt serving as a critical building block in advanced pharmaceutical research and development. This compound is valued for its role as a versatile intermediate in the synthesis of complex molecules, particularly those targeting central nervous system pathways. It is primarily sought by research chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for creating novel therapeutic agents and reference standards.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in neurological and psychiatric research.
• Chemical Reference Standard: Used for analytical method development, validation, and quality control in API (Active Pharmaceutical Ingredient) manufacturing.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization for new therapeutic targets.
• Process Chemistry: Serves as a starting material or intermediate in scale-up and route development for potential commercial APIs.
• Biochemical Research: Utilized in the study of enzyme inhibitors and receptor ligands due to its indoline scaffold.

Basic Information

Product Name	1-Methyl-2,3-Dihydro-1H-Indol-5-Ylamine Dihydrochloride
CAS No.	1240527-25-6
Molecular Formula	C9H14Cl2N2
Molecular Weight	233.13 g/mol
Synonyms	5-Amino-1-methyl-2,3-dihydro-1H-indole dihydrochloride; 1-Methyl-2,3-dihydro-1H-indol-5-amine dihydrochloride; 5-Amino-1-methylindoline dihydrochloride; 1-Methyl-5-aminoindoline dihydrochloride; 1240527-25-6; 5-Amino-1-methylindoline hydrochloride (1:2); 1-Methylindolin-5-amine dihydrochloride
EINECS	Contact for details

Quality Control

Our 1-Methyl-2,3-Dihydro-1H-Indol-5-Ylamine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the stringent requirements for research and development use. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.