Description

Methyl 6-Bromoindoline-4-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its brominated indoline core structure. This compound is of significant value for its role as a versatile building block in the synthesis of complex bioactive molecules, particularly in medicinal chemistry. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, including kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel drug candidates, particularly those targeting specific enzyme pathways.
• Medicinal Chemistry Research: Used as a core scaffold or building block for constructing libraries of compounds in hit-to-lead and lead optimization studies.
• Organic Synthesis: Serves as a versatile reagent for introducing the bromo-indoline moiety into more complex molecular architectures via cross-coupling and other functionalization reactions.
• Agrochemical Development: Potential application as an intermediate in the synthesis of new crop protection agents and pesticides.
• Material Science Research: May be investigated as a monomer or precursor for specialty polymers and advanced organic materials.

Basic Information

Product Name	Methyl 6-Bromoindoline-4-Carboxylate
CAS No.	1240523-98-1
Molecular Formula	C10H10BrNO2
Molecular Weight	256.10 g/mol
Synonyms	6-Bromoindoline-4-carboxylic acid methyl ester; Methyl 6-bromo-2,3-dihydro-1H-indole-4-carboxylate; 1H-Indole-4-carboxylic acid, 6-bromo-2,3-dihydro-, methyl ester; 6-Bromo-2,3-dihydro-1H-indole-4-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 6-Bromoindoline-4-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.