Description

5-Fluoro-4-(Methyloxy)-1H-Indazol-3-Amine CAS NO 1240518-48-2 is a high-purity indazole derivative, a crucial advanced pharmaceutical intermediate for modern drug discovery and development. Its value lies in its role as a versatile building block for synthesizing novel, biologically active compounds targeting a range of therapeutic areas. This product is essential for research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly those developing kinase inhibitors and other small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel drug candidates, particularly kinase inhibitors.
• Medicinal Chemistry Research: Used as a core scaffold or building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Reagent: Employed in biochemical assays and as a tool compound for probing biological pathways and target validation.
• Organic Synthesis: Serves as a versatile intermediate for the synthesis of more complex heterocyclic compounds and functionalized indazole derivatives.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.

Basic Information

Product Name	5-Fluoro-4-(Methyloxy)-1H-Indazol-3-Amine
CAS No.	1240518-48-2
Molecular Formula	C8H8FN3O
Molecular Weight	181.17 g/mol
Synonyms	5-Fluoro-4-methoxy-1H-indazol-3-amine; 3-Amino-5-fluoro-4-methoxy-1H-indazole; 4-Methoxy-5-fluoro-1H-indazol-3-amine; 1240518-48-2; 5-Fluoro-4-methoxyindazol-3-ylamine; 5-Fluoro-4-methoxy-1H-indazol-3-amine; 5-Fluoro-4-methoxy-1H-indazol-3-ylamine
EINECS	Contact for details

Quality Control

Our 5-Fluoro-4-(Methyloxy)-1H-Indazol-3-Amine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive analytical data, including HPLC purity, NMR, and MS confirmation. A Certificate of Analysis (COA) detailing all specifications is available with every shipment and upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.