Description

tert-Butyl 3-Amino-4-Methoxy-1H-Indazole-1-Carboxylate is a high-purity, protected indazole derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its primary value lies in providing a versatile and reactive scaffold for constructing complex heterocyclic molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable building blocks for drug discovery programs.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies due to its modifiable amino and methoxy functional groups.
• Agrochemical Synthesis: Intermediate in the development of new herbicides, fungicides, and plant growth regulators.
• Chemical Biology Probes: Serves as a precursor for fluorescent tags or affinity probes to study biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of proprietary compounds and active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for methodological development in heterocyclic chemistry.

Basic Information

Item	Detail
Product Name	tert-Butyl 3-Amino-4-Methoxy-1H-Indazole-1-Carboxylate
CAS No.	1240518-05-1
Molecular Formula	C₁₃H₁₇N₃O₃
Molecular Weight	263.29 g/mol
Synonyms	1-Boc-3-amino-4-methoxy-1H-indazole; tert-Butyl 3-amino-4-methoxyindazole-1-carboxylate; 3-Amino-4-methoxy-1H-indazole-1-carboxylic acid tert-butyl ester; 1H-Indazole-1-carboxylic acid, 3-amino-4-methoxy-, 1,1-dimethylethyl ester; Boc-3-amino-4-methoxyindazole; 1240518-05-1; 3-Amino-4-methoxyindazole Boc-protected
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-Amino-4-Methoxy-1H-Indazole-1-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. Certificates of Analysis (COA) are available for every batch, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.