Description

n-Acetyl-S-(3,4-Dihydroxybutyl)-L-Cysteine-D7 (Mixture Of Diastereomers) is a deuterium-labeled, acetylated cysteine derivative, serving as a crucial stable isotope-labeled internal standard for advanced analytical chemistry. This high-purity compound is essential for ensuring the accuracy and reliability of quantitative mass spectrometry analyses, particularly in metabolomic and pharmacokinetic studies. It is primarily utilized by research institutions, pharmaceutical developers, and contract research organizations (CROs) engaged in biomarker discovery, drug metabolism research, and high-precision bioanalytical method development.

Application

• Quantitative Mass Spectrometry Internal Standard: Serves as a critical reference compound for the accurate quantification of its non-labeled counterpart or related metabolites in complex biological matrices via LC-MS/MS and GC-MS.
• Biomarker Research & Validation: Used in the development and validation of highly sensitive assays for detecting and measuring specific cysteine adducts or metabolic pathway intermediates.
• Drug Metabolism and Pharmacokinetics (DMPK): Enables precise tracking of drug disposition, biotransformation, and excretion in preclinical and clinical studies by acting as a stable isotope-labeled tracer.
• Toxicological Studies: Facilitates research into chemical exposure and toxicity mechanisms by allowing for the specific measurement of metabolic products related to glutathione conjugation pathways.
• Clinical Diagnostics Development: Supports the creation of standardized, high-fidelity diagnostic tests for metabolic disorders or exposure biomarkers.
• Academic & Industrial Research: Provides a key tool for fundamental biochemical research involving sulfur amino acid metabolism, redox biology, and protein modification studies.

Basic Information

Product Name	n-Acetyl-S-(3,4-Dihydroxybutyl)-L-Cysteine-D7 (Mixture Of Diastereomers)
CAS No.	1240398-27-9
Molecular Formula	C9H10D7NO5S
Molecular Weight	Contact for details
Synonyms	N-Acetyl-S-(3,4-dihydroxybutyl)-L-cysteine-d7; Acetylcysteine D7 derivative; S-(3,4-Dihydroxybutyl)-N-acetyl-L-cysteine-d7; Mercapturic Acid Derivative D7; N-Acetyl-S-(3,4-dihydroxybutyl)cysteine-d7; Stable Isotope Labeled Cysteine Adduct; Deuterated N-Acetyl-S-(3,4-DHB)-L-Cys; L-Cysteine, N-acetyl-S-(3,4-dihydroxybutyl)-, d7-
EINECS	Contact for details

Quality Control

Every batch of our n-Acetyl-S-(3,4-Dihydroxybutyl)-L-Cysteine-D7 is manufactured and analyzed under strict quality systems to ensure exceptional purity and isotopic enrichment, meeting the exacting requirements of analytical reference standards. We provide comprehensive Certificates of Analysis (COA) detailing purity (by HPLC), isotopic purity (by MS), and identity confirmation (by NMR and/or IR). Our quality commitment aligns with the standards expected for research-grade and internal standard applications in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain integrity. Allow the sealed vial to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Isotopic Purity (MS)	≥ 98 atom % D
Chemical Purity	≥ 90% (by NMR)
Water Content (KF)	≤ 2.0 %
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.