Description

2-Fluoro-5-(Pentafluorosulfur)Benzylbromide is a high-value, multi-functional fluorinated building block essential for advanced chemical synthesis. Its unique structure, featuring both a reactive benzyl bromide group and a pentafluorosulfur (SF5) moiety, makes it a critical intermediate for introducing fluorinated aromatic systems with enhanced stability and lipophilicity. This compound is primarily sought after by R&D and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients, as well as in materials science for creating specialty polymers and liquid crystals.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-infectives, where the SF5 group can improve metabolic stability and membrane permeability.
• Agrochemical Active Ingredient Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the SF5 group's ability to enhance biological activity and environmental persistence.
• Advanced Materials Precursor: Serves as a monomer or cross-linking agent in the synthesis of specialty polymers, liquid crystals, and electronic materials that require fluorinated aromatic units for thermal stability, chemical resistance, or specific optical properties.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create sophisticated ligands for catalysis, where the electron-withdrawing SF5 group can finely tune the metal center's electronic properties.
• Fluorine Chemistry Research: A valuable reagent for academic and industrial research exploring the synthesis and reactivity of pentafluorosulfur-substituted aromatic compounds.

Basic Information

Product Name	2-Fluoro-5-(Pentafluorosulfur)Benzylbromide
CAS No.	1240256-82-9
Molecular Formula	C7H3BrF6S
Molecular Weight	289.06 g/mol
Synonyms	1-(Bromomethyl)-2-fluoro-5-(pentafluoro-λ6-sulfanyl)benzene; α-Bromo-2-fluoro-5-(pentafluorosulfur)toluene; 2-Fluoro-5-(SF5)benzyl bromide; (2-Fluoro-5-(pentafluorosulfanyl)phenyl)methyl bromide; 5-(Bromomethyl)-2-fluoro-1-(pentafluorosulfanyl)benzene; 2-Fluoro-5-pentafluorosulfanylbenzyl bromide; Bromo(2-fluoro-5-pentafluorosulfanylphenyl)methane
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-5-(Pentafluorosulfur)Benzylbromide is manufactured and analyzed under strict quality management protocols to ensure consistency and purity for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay purity and impurity profiles. Our quality systems are designed to support cGMP compliance for pharmaceutical development, and we can accommodate custom purity specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when prolonged exposure is anticipated to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.