Description

1,1,1-Trifluoro-n-[(11Br)-4-Oxido-2,6-Bis[2,4,6-Tris(1-Methylethyl)Phenyl]Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin-4-Yl]-Methanesulfonamide is a sophisticated organophosphorus compound featuring a sterically hindered dinaphthodioxaphosphepin core, designed for high-performance applications. Its unique structure, incorporating a trifluoromethanesulfonamide group, makes it a valuable ligand precursor or catalyst component in advanced synthetic chemistry. This specialty chemical is essential for researchers and process chemists in the pharmaceutical and fine chemical industries developing novel synthetic routes, particularly for asymmetric transformations.

Application

• Ligand for Asymmetric Catalysis: Serves as a precursor for chiral phosphine-oxazoline (PHOX) or related hybrid ligands in enantioselective hydrogenation, cross-coupling, and C-H activation reactions.
• Advanced Material Synthesis: Used in the research and development of novel organic electronic materials and functional polymers where precise steric and electronic control is required.
• Pharmaceutical Intermediate: Acts as a key building block or catalyst in the multi-step synthesis of complex, high-value active pharmaceutical ingredients (APIs).
• Organometallic Chemistry: Employed in the preparation of transition metal complexes for catalytic studies and mechanistic investigations.
• Methodology Development: Utilized by academic and industrial R&D laboratories for developing new catalytic protocols and exploring reaction mechanisms.

Basic Information

Product Name	1,1,1-Trifluoro-n-[(11Br)-4-Oxido-2,6-Bis[2,4,6-Tris(1-Methylethyl)Phenyl]Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin-4-Yl]-Methanesulfonamide
CAS No.	1239466-15-9
Molecular Formula	C49H48BrF3NO5PS
Molecular Weight	930.83 g/mol
Synonyms	1,1,1-Trifluoro-N-[(11bR)-4-oxido-2,6-bis[2,4,6-tris(propan-2-yl)phenyl]dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-yl]methanesulfonamide; (R)-3,5-Di-tert-butyl-4-methoxyphenylbis(2,4,6-triisopropylphenyl)phosphine; Sterically Hindered Phosphine-Sulfonamide Ligand Precursor; Br-DINAP(O) Derivative; Triflyl-Protected Phosphine Oxide; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of our specialty organophosphorus compounds is produced and analyzed under strict quality protocols. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles to ensure consistency for your critical research and development. Our quality systems are designed to support cGMP and ISO 9001 standards for traceability and reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its chemical nature as a fluoride/strong alkali-sensitive compound, keep away from incompatible materials. For long-term storage, consider maintaining under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.